Plant Gel-Mediated Synthesis of Gold-Coated Nanoceria Using Ferula gummosa: Characterization and Estimation of Its Cellular Toxicity toward Breast Cancer Cell Lines

In this study, a novel method using Ferula gummosa gums as capping agent was used to synthesize the nanoceria for first time. The economical and performed at room temperature. Furthermore, it coated with gold (Au/nanoceria) fully characterized X-ray powder diffraction (XRD), field emission scanning electron microscopy energy-dispersive spectroscopy (FESEM-EDX), Fourier-transform infrared (FTIR), dynamic light scattering (DLS), zeta potential (ζ potential). crystallite size obtained from results 28.09 nm Au/nanoceria. (EDX) analysis of Au/nanoceria revealed compositional constituents product, which display purity cell toxicity properties non-doped Au-coated were identified by MTT on breast cancer line (MCF7). Additionally, human foreskin fibroblast cells (HFF) normal line. cytotoxicity indicated that toxicological effect significant while having little toxic cells. clearly shows dependence dose time, so, increasing Au/nanoceria, death also increases.